IL10 and Behcet disease: In 2010 the first genome-wide association study (GWAS) in BD cohorts of Turkish and Japanese origin demonstrated association of various variants in the known HLA-B51 domain, and two new association signals, mapping to the interleukin-10 (IL10), and the IL-23 receptor–IL-12 receptor Beta2 (IL23R–IL12RB2) locus [10,11].