Pediatric low grade astrocytoma and ependymoma cell lines showed high percentages of cells expressing VEGFR-1, FGFR-1, EGFR, HGFR and RON (respectively 52–77%, 34–51%, 63–90%, 83–98%, 65–95%, compared to isotype controls, Fig. 2A). This evidence concerns the gene FLT1 and astrocytoma (excluding glioblastoma).