BRAF and melanoma: Although both RGP cell lines have similar levels of stress-induced CXCR3 regardless of BRAF status, stressed WM35 cells had much higher levels of IL-8 than stressed BOWES cells (Fig. 4D, P≤0.0001), consistent with findings that IL-8 levels are increased in human melanoma cell lines containing the BRAFV600E mutation [43].