For example, the expression of all three CRIM1 regions are well correlated within both normal and tumor tissue types, yielding a correlation coefficient (r) of 0.95 between the first two regions (CRIM1:1 vs CRIM1:2) that are separated by over 50 kb and r = 0.77 for the first and third loci (CRIM1:1 vs CRIM1:7), separated by ~75 kb. The gene discussed is CRIM1; the disease is neoplasm.