Procalcitonin and C-reactive protein have been widely used as biomarkers in critical care.[11,16] Although C-reactive protein and procalcitonin can increase the likelihood of a sepsis diagnosis,[17] Procalcitonin is associated with poor long-term neurologic outcomes and mortality in patients achieving ROSC after OHCA; however, C-reactive protein was not associated with outcomes.[16] In addition, elevated levels of procalcitonin and C-reactive protein do not correlate with infection in the early stage of post-cardiac arrest syndrome.[16]. This evidence concerns the gene CRP and infection.