RORA and post-traumatic stress disorder: 2013) referenced evidence of the role of RORA in protection against neurodegeneration in the face of oxidative stress (Jolly et al. 2012). They hypothesized that RORA could modify neurodegeneration and functional abnormalities in areas of the brain associated with PTSD and related psychopathology. The authors also proposed alternative biological mechanisms, such as the involvement of RORA in processes related to circadian rhythms and steroid hormones that, in turn, have been shown to be dysregulated in cases of PTSD (Jetten 2009; Rasmusson et al. 2010; Germain 2013; Miller et al. 2013).