Using 10 freshly collected clinical HCC samples, we found that miR-432 expression was inversely correlated with the expression of β-catenin(r = −0.688, P = 0.002), LRP6 (r = −0.872, P = 0.007), TRIM29 (r = −0.775, P = 0.004), Pygo2 (r = −0.663, P = 0.014) (Figure 6A and 6B). This evidence concerns the gene LRP6 and hepatocellular carcinoma.