A newly study reveal that miR-432 induced neurite projections, arrested cells in G0–G1, reduced cell proliferation and could significantly repress the expression of NESTIN/NES, RCOR1/COREST and MECP2,which suggest that miR-432 may play an important role in regulating neuronal differentiation of human neuroblastoma cells [27]. The gene discussed is MECP2; the disease is neuroblastoma.