RNASET2 and ovarian carcinoma: Furthermore, molecular correlates of RNASET2-associated biological responses were recently provided by our group following investigations in an ovarian cancer cell-based xenograft model, where in vivo gene expression profiling disclosed a significant RNASET2-dependent modulation of expression for gene categories related to immune response functions [6], strongly suggesting a role for RNASET2 as an alarmin-like molecule.