RNASET2 and ovarian carcinoma: We have here demonstrated that the lack of RNASET2 was associated with both an increase in anchorage-independent growth in agar (in line with our previous demonstration that RNASET2 expression is inversely correlated to ovarian cancer cell growth in in vivo mouse models) [5, 6] and a different pattern of cell migration and invasion in Matrigel, which was never assessed before.