MKI67 and cancer: We also found that IL-6 neutralization markedly diminished the up-regulation of MKI67 (4T1, 1.21 ± 0.22; CT26, 1.27 ± 0.31) and PCNA (4T1, 1.54 ± 0.9; CT26, 1.20 ± 0.46) induced by ADSCs in cancer cells (Figure 6B).