In support of this, ectopic expression of miR-204 lowered the level of XRN1 protein in all the PCa cell lines tested (Fig. 3B), whereas introduction of the miR-204 inhibitor raised level of XRN1mRNA (Fig. 3C), suggesting that miR-204 is a repressor of XRN1 expression in PCa cells. Here, XRN1 is linked to posterior cortical atrophy.