To further investigate whether MMP-9 and VEGF-C activity is necessary for the migration and invasion of ACC-M cell, we examined the influence of inhibitor I, a specific inhibitor of MMP-2 and MMP-9, and the receptor of VEGF-C (VEGFR-3, 200 ug/mL, 100 uL) on cells. Here, MMP9 is linked to adrenal cortex carcinoma.