TYR and oculocutaneous albinism type 1A: The combination of tools resulted in the indication of four, two and one nsSNPs as the most deleterious mutations in the TYR, TYRP1 and P proteins of the gene, which are associated with oculocutaneous albinism type IA (OCA1A) [41], type III (OCA3) [42] and type II (OCA2) [40], respectively.