With regard to the AML associated genetic alterations (Table 2), higher BM Robo4 expression was closely associated with ASXL1 mutation (15.2% versus 6.7%, P = 0.0489) but negatively associated with CEBPA mutation (6.1% versus 18.5%, P = 0.0076). The gene discussed is ASXL1; the disease is acute myeloid leukemia.