CADM1 and lung adenocarcinoma: We found that the SE score improved over stage Ia/b alone in a meta-analysis across 765 stage I lung adenocarcinomas (SE score+stage vs stage: p = 0.025), whereas CADM1 expression made no improvement over stage Ia/b (CADM1 expression+stage vs stage: p = 0.13, Fig. 5C).