VIM and colorectal cancer: At the same time, previous studies showed that EIF5A2 promotes cell invasion/metastasis and epithelial-mesenchymal transition (EMT) through activating MTA1/C-MYC in colorectal cancer.[8] MTA1 and C-MYC, as well as the EMT program, were also involved in regulation of GC metastasis.[26–28] We therefore examined MTA1, C-MYC and two EMT-associated markers, E-cadherin and vimentin.