Within somatic mutations recalled from paired normal-tumor exome sequencing samples of 305 HNSC and 243 LUSC, RAD52 was rarely mutated somatically (point mutations and insertions deletions), with only 2 HNSC (0.60% of tumors) and one LUSC (0.40% of tumors) patients harbouring a somatic missense variant, and no somatic insertion or deletion observed. The gene discussed is RAD52; the disease is neoplasm.