About histogenesis of this type of cells in liver, they had a similar expression of almost all osteoclast markers of bone, including CD68, receptor activator of nuclear factor-kappa B (RANK), and RANK ligand (RANKL), suggesting that osteoclast-like cells in liver cancer had similar histogenesis of osteoclastogenesis in bone [2, 4, 12]. The gene discussed is CD68; the disease is liver cancer.