The first SNP is non-synonymous, in which the amino acid arginine is changed to tryptophan, while the second one is located at 3′-UTR of SLC30A8. We genotyped these two SNPs in the Malay subjects with NGT and T2D, and data showed the genotype distributions of these two SNPs in Hardy-Weinberg equilibrium (HWE). The gene discussed is SLC30A8; the disease is type 2 diabetes mellitus.