EWSR1 and amyotrophic lateral sclerosis: Therefore, it was of particular interest that from our proteomic screen, we identified six binding partners of Oxr1 that present either a variant or a mutation associated with ALS: FUS, TDP-43 as well as hnRNPA2B1, hnRNPA1, EWSR1 and PRPH (1,11,63,96–99).