For FGFR1, the changes were more varied, including hotspot point mutations (p.N546K, p.K656E); FGFR1–TACC1 fusions similar to those seen in adult GBM [61]; and a novel internal duplication of the kinase domain [termed TKD-duplicated or FGFR1 internal tandem duplication (FGFR1-ITD)] [32, 67]. This evidence concerns the gene FGFR1 and glioblastoma.