To this end, we measured the expression of the 18 known HDAC genes and of 6genes encoding transciptional co-factors in 50 samples representing 3histopathologically identified gliomas, namely W.H.O. (World Health Organization) gradeII oliodendrogliomas (ODII), grade III oliodendrogliomas (ODIII), grade IV glioblastoma(GL), and in 15 control brain samples from epilepsia-operated patients. The gene discussed is HDAC9; the disease is central nervous system cancer.