PRKN and obesity due to melanocortin 4 receptor deficiency: Furthermore, oligonucleotide microarray data from cerebellar tissue of 6-month-old Atxn2-KO mice with an obesity phenotype [63, 64] documented transcript levels of Fbxw8 (oligonucleotide spot 1436732_s_at, log2-fold-change 0.16) and Park2 (oligonucleotide spot 1449975_a_at, log2-fold-change 0.28) without significant alterations.