The effects of light-cola drinking (striking increase in Trx1 and Prx2, a robust trend to hypertriglyceridemia, decrease in plasma level of CoQ10 and increase in HOMA-IR, reduction in β cells’ size, increase in α/β-cell ratio, increase in α cells’ size, decrease in α cells’ number) might suggest the development of an oxidative stress condition as well. The gene discussed is TXN; the disease is hypertriglyceridemia.