MTOR and cancer: Seeking independent verification that the “confirmed S6-P positives” are enriched in regulators of mTORC1 we utilized the Achilles dataset [35; release 2.4.1 available at www.broadinstitute.org/achilles)] which enabled an inquiry of how shRNA mediated depletion of “confirmed S6-P positives” affects the proliferation/viability of a large number of cancer cell lines in comparison to depletion of mTOR.