RP1 and metastatic malignant neoplasm in the lymph nodes: The staining intensity of IGFBP-rP1 was inversely correlated with histological grade (r=−0.161, P=0.017), lymph-node metastasis (r=−0.174, P=0.011), and TNM stage (r=−0.149, P=0.028) (Table 1).