There were no significant differences between the L-TME and R-TME groups in the adjusted analysis using one-to-one propensity score matching, and no relevant differences were found between the 2 groups in terms of age, sex, BMI, American Society of Anesthesiologists score, tumor location, operation method, pathologic TNM stage, history of previous abdominal surgery, mean preoperative carcinoembryonic antigen levels, and neoadjuvant or adjuvant treatment. Here, CEACAM5 is linked to neoplasm.