BUD23 and Williams syndrome: In a similar fashion, we also identified several significant genes (i.a. DNAJC30 (DnaJ (Hsp40) homolog, subfamily C, member 30) and WBSCR22 (Williams Beuren syndrome chromosome region 22)) on chromosome 25 associated with the ratio of BHBA (T2/T1) with p-values smaller than 1. 69×10-6.