When analyzing gout as the phenotype, two loci reached genome-wide significance: a novel association with an exonic SNP in ALDH16A1 (P = 1.4 × 10−16), and a Q141K variant within ABCG2 (P = 2.82 × 10−12), a gene previously reported to be associated with gout and serum uric acid levels. This evidence concerns the gene ABCG2 and gout.