Four loci reached genome-wide significant association when evaluating association with serum uric acid levels: the same ALDH16A1 SNP found with gout (P = 4.5 × 10−21), a novel association with the chromosome 1 centromere (P = 4.5 × 10−16), as well as previously reported signals at SLE2A9 (P = 1.0 × 10−80) and ABCG2 (P = 2.3 × 10−20). The gene discussed is ALDH16A1; the disease is gout.