VIM and juvenile idiopathic arthritis: Additionally, further prospective evaluation is warranted to determine the prevalence, significance, and predictive value of specific autoantibodies to citrullinated proteins/peptides (i.e., anti-citrullinated type II collagen antibodies, anti-citrullinated vimentin, and others) and elucidate their role in JIA in general and in different subtypes of the disease [34, 38].