The immunohistochemical detection of the KAI1/CD82 protein expression in the two groups revealed that the positive expression rate of the KAI1/CD82 protein in the non-neoplastic nasopharyngeal tissues (21/30; 70.0%) was significantly higher than that of NPC group (31/70; 44.3%), and the χ2 test revealed a statistically significant difference in KAI1/CD82 protein expression between the two groups (Fig. 3) (P<0.05). The gene discussed is CD82; the disease is nasopharyngeal carcinoma.