Stacpoole (10) stated that the following criteria should be fulfilled in order to diagnose glucagonoma syndrome: i) Detection of a tumour by direct visualisation or imaging examination; ii) evidence that the tumour demonstrates a preponderance of glucagon-containing cells; iii) an increase in the level of basal circulating immunoreactive glucagon; and iv) the presence of a skin rash, glucose intolerance and hypoaminoacidaemia, alone or in combination. Here, GCG is linked to Glucose intolerance.