Shirai et al (107) determined that the p53 SNP Arg72Pro was associated with a poor prognosis in gastric cancer (107), while Kim et al (106) identified that the TP53 codon 72 SNP was predictive of the chemotherapy response and that it was associated with the time to progression in advanced gastric cancer patients treated with paclitaxel and cisplatin chemotherapy. Here, TP53 is linked to gastric cancer.