For example, García-González et al (109) determined that pro- and anti-inflammatory cytokine gene polymorphisms, such as IL1B, TNFA, LTA, IL6, IL12p40, IL4, IL1RN, IL10 and TGFB1, may not be relevant in determining the prognosis of gastric adenocarcinoma patients. This evidence concerns the gene TGFB1 and gastric adenocarcinoma.