MYC and neoplasm: The co-IF/FISH data show that the 8q24/Myc locus is amplified in all four tumors, and that CENP-A domains are enriched on one of these 8q24 loci ranging from 33 to 78% of tumor cells, depending on the donor (Figure 8C, lowest set of panels for representative images of normal versus tumor, white arrow points to co-localization, quantification in Table 7).