Just recently it was shown that disruption of the TAB1 (transforming growth factor-β (TGFβ-activated protein kinase 1 (TAK1)-binding protein 1) /p38α interaction by cell-permeable peptides limits myocardial ischemia/reperfusion injury by reduction of apoptotic cardiomyocytes and infarct size when applied 30 min before reperfusion (Wang et al., 2013). Here, TAB1 is linked to myocardial ischemia.