Non-GCB type DLBCL cell-line Oci Ly10, GCB type DLBCL cell-line Oci Ly19 as well as normal peripheral blood mononuclear cells (PBMC, controls) were cultured in the presence of increasing concentrations of CX-4945 (2.5, 5 and 10 μM) and the amount of apoptosis was then measured after 24 hours by Annexin V staining and fluorescence activated cell sorting (FACS) analysis. The gene discussed is ANXA5; the disease is diffuse large B-cell lymphoma.