D, respectively) and no stromal expression in stage D. Finally, ADAMTS-20 also exhibited low staining in the longitudinal layer of Muscularis Externa in healthy colon specimens (Fig. 2B, Healthy), while in CRC it was detected only in cancer cells of stage B and mainly of stage C specimens (arrowheads in Fig. 2B, St.B and St. The gene discussed is ADAMTS20; the disease is colorectal carcinoma.