Consistent with the univariate analysis, the ARMS2 SNP was associated with early AMD in the models adjusted for potential risk factors (Model 1, p = 0.002; Model 2, p = 0.001, Table 4) and any AMD (Model 1, p = 0.001; Model 2, p <0.001, Table 4). This evidence concerns the gene ARMS2 and age-related macular degeneration.