For the ARMS2 genotype, compared to phakic eyes with the CC genotype, the risk of having early AMD was higher both in pseudophakic/aphakic eyes (genotype CT: OR = 1.69, 95% CI: 1.18–2.42; TT: OR = 2.48, 95% CI: 1.44–4.27) and phakic eyes (genotype CT: OR = 1.28, 95% CI: 1.04–1.57; TT: OR = 1.64, 95% CI: 1.09–2.46). The gene discussed is ARMS2; the disease is age-related macular degeneration.