However, a significant step towards taking curcumin to clinic, Vacurin amphipathic vaginal cream—a uniform colloidal solution of curcumin, was shown to selectively eliminate a variety of HPV (+) cervical cancer cells, suppress the transforming antigen E6 and concomitantly induce p53, suppressing expression of EGFR [74]. This evidence concerns the gene TP53 and cervical cancer.