Slug and N-cadherin, known players of EMT, induced by TGF-β are involved in migration and invasion [9], and TGF-β-mediated induction of N-cadherin involves Pin1 (peptidyl-prolyl cis/trans isomerase), known to play an important role in TGF-β-induced migration and invasion of cancer cells [10]. This evidence concerns the gene CDH2 and cancer.