Although, we were successful in identifying few variants with probable regulatory functions from the studied GWAS loci (which was the main aim of this study), we could not be conclusive for their association with IBD or other IMDs, due to the limitation of our in-silico method (none of the tools were disease specific; regulatory elements (e.g. TF binding sites, eQTLs) mostly for certain cell types from ENCODE). The gene discussed is TF; the disease is inflammatory bowel disease.