MRA-neg, Patients not treated by mineralocorticoid receptor antagonist; MRA-plus, Patients treated by mineralocorticoid receptor antagonist; AHT, arterial hypertension; ICM, ischemic cardiomyopathy; Creat: creatinine; LVEF, left ventricular ejection fraction; BNP, brain natriuretic peptide; Gal-3, Galectin-3; HR: heart rate; NYHA, New York Heart Association classes; SGOT, serum glutamic oxaloacetic transaminase; ARA II, angiotensin II receptor antagonists; AVK drugs, Anti vitamin K drugs; ACE inhibitors, angiotensin-converting-enzyme inhibitors. The gene discussed is ACE; the disease is ischemic cardiomyopathy.