Each of the unique BP signature genes in the Illumina cohorts, 6 for SBP (TAGLN2, BHLHE40, MYADM, SLC31A2, DUSP1, and MCL1), 1 for DBP (BHLHE40) and 1 for HTN (SLC31A2), replicated in the FHS. The gene discussed is DUSP1; the disease is hypertensive disorder.