This was further confirmed by CD45 staining, where no CD45 + cells were detected in either the control or in the exposed animals when examining their cerebral cortices and dentate gyri, whereas CD45 staining was evident in the positive control (sagittal brain sections from the PSAPP mouse model of Alzheimer’s Disease (data not shown)). This evidence concerns the gene PTPRC and early-onset autosomal dominant Alzheimer disease.