Double cytokine producing T-cells IL-2+IFN-γ+ did distinguish between past tuberculosis in comparison with healthy EliSpot-IGRA-negative controls (median 2.5 SFC/ 200.000 PBMC versus 0 SFC/ 200.000 PBMC, p = 0.0075, Fig. 3E). The gene discussed is IL2; the disease is tuberculosis.