IL2 and tuberculosis: Analysing the ESAT-6-induced cytokine response in the FluoroSpot system, the SFC of total IL-2+ secreting cells were significantly higher in tuberculosis or LTBI in comparison with the healthy EliSpot-IGRA-negative control group (median 9.5 SFC/200.000 PBMC versus 2 SFC/200.000 PBMC, p = 0.0015 and 4 SFC/ 200.000 PBMC versus 2 SFC/ 200.000 PBMC, p = 0.0159, respectively, Fig. 3A).