In cells isolated from healthy donors, the expression of CCL2 (healthy versus APS; 0.136 ± 0.052 versus 0.023 ± 0.008, P = 0.03), IL-1β (1.239 ± 0.147 versus 0.224 ± 0.066, P = 0.0001), and IL-6 (0.163 ± 0.059 versus 0.033 ± 0.008, P = 0.03) was higher than in APS monocytes. Here, IL1B is linked to autoimmune polyendocrinopathy.