While there were no further severe or frequent hypoglycemic events on liraglutide therapy and her weight increased to 93 kg (BMI 33), with the addition of an SGLT2 inhibitor to her regimen her weight returned to 80 kg (BMI 28) with maintenance of excellent glycemic control (HbA1c 6.6%) which was achieved without the complication of severe or frequent hypoglycemia. Here, SLC5A2 is linked to Hypoglycemia.