On the other hand, the receptor of oxLDL, lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) identified as the main endothelial receptor for oxLDL and also present in macrophages and smooth muscle cells (SMC), activates a proatherogenic cascade by inducing endothelial dysfunction, SMC proliferation, apoptosis, and the transformation of macrophages into foam cells and platelet activation via NF-κB activation [48]. The gene discussed is OLR1; the disease is endothelial dysfunction.