E. G. is a fifty-year-old, black female with a past history of Crohn's disease, diagnosed at the age of 19 with subsequent intestinal resection at the age of 21, and a history of ischemic stroke who presented with left sided weakness, mild aphasia, and mild dysarthria (NIHSS = 3) outside the 4.5-hour window for treatment with tPA. The gene discussed is PLAT; the disease is Aphasia.