A genome-wide analysis found a SNP of C1q receptor C1qRp (CD93) constituting a risk factor for coronary artery disease, which could be confirmed in patients with familial hypercholesteremia (van der Net et al., 2008) and polymorphisms for mannose binding lectin (MBL) with decreased levels of the protein went along with more coronary artery disease and increased carotid plaque (Madsen et al., 1998; Hegele et al., 2000; Best et al., 2004). The gene discussed is MBL2; the disease is coronary artery disorder.