At the same time antidepressant treatment reversed these MD-associated astroglial deficits as an increase in expression of astroglial markers GFAP, S100β and aldehyde dehydrogenase 1 family, member L1 (ALDH1L1) were revealed in the post-mortem analysis (Barley et al., 2009). Here, ALDH1L1 is linked to Menkes disease.