ESRD patients with DM and PPAR-γ C161T CT genotype and CC genotype also had significantly higher risk of mortality (the former, HR 1.93, 95% confidence interval [CI] 1.36–2.73; P < 0.001; the latter, HR 2.86, 95% CI 2.11–3.86; P < 0.001) than those with TT genotype. This evidence concerns the gene PPARG and diabetes mellitus.